Grip strength: the vital sign hiding in your hand
Weaker grip goes with shorter life in huge studies across the world. What that does and does not mean, and what you can actually change.
The verdict
“Weaker grip predicts a higher risk of death”
B · ModerateEvidence at a glance
| Claim | Grade | Refs |
|---|---|---|
| Weaker grip is associated with higher risk of death from any cause and from cardiovascular disease | B · Moderate | 1, 2 |
| Grip strength predicted all-cause and cardiovascular death better than systolic blood pressure (one multinational cohort) | B · Moderate | 1 |
| Progressive resistance training increases muscle strength in older adults | A · Strong | 5 |
| Making your grip stronger will make you live longer | D · Unsupported | 1 |
Grades follow our method. A strong link between two things is not proof that one causes the other.
Key points
- In large studies, weaker grip goes with higher risk of death from any cause and from heart disease.
- In one 17-country study it predicted death better than systolic blood pressure.
- Grip is a window onto whole-body muscle strength, which is now the core of how sarcopenia is defined.
- Strength training reliably makes older adults stronger; whether that lengthens life has not been tested directly.
Squeeze a dynamometer — a hand-held gauge that measures how hard you can grip — and you produce one number in a few seconds. Over the past decade that number has turned out to say a surprising amount about your future health.
What the big studies found
The PURE study measured grip strength in nearly 140,000 adults aged 35 to 70 across 17 countries, from high-income to low-income, and followed them for a median of four years. After adjusting for other risk factors, every 5 kg lower grip strength was associated with a 16% higher risk of death from any cause (hazard ratio 1.16), with similar associations for cardiovascular death, heart attack and stroke. Grip strength was a stronger predictor of all-cause and cardiovascular death than systolic blood pressure.[1]
The UK Biobank study of about half a million people aged 40 to 69 found the same pattern: lower grip went with higher risk of death from any cause and from cardiovascular disease, respiratory disease and several cancers, in both women and men. Adding grip strength to a standard office risk score modestly improved its ability to predict death.[2]
Why a hand would predict the whole body
Grip is not special in itself. It is a quick, cheap window onto overall muscle strength — and muscle strength now sits at the center of how doctors define sarcopenia, the age-related loss of muscle strength and mass. The revised European consensus made low muscle strength the key characteristic of sarcopenia,[3] and the Asian Working Group for Sarcopenia defines low strength as a handgrip below 28 kg for men and 18 kg for women.[4]
From an orthopedic surgeon's point of view, this fits what clinics see every day. Weak muscles mean less protection for joints, slower recovery after surgery and a narrower margin before ordinary tasks — stairs, getting up from a chair, carrying shopping — become hard.
The part that is easy to get wrong
These studies show an association. Stronger people live longer, but they may also be healthier in many other ways that the statistics cannot fully separate. The PURE authors themselves wrote that further research is needed to test whether improving strength actually reduces death and cardiovascular disease.[1] That is why the claim "a stronger grip will make you live longer" is graded D here: it has not been tested, not disproved.
What you can change
The good news is that strength itself responds to training at any age. A Cochrane review of 121 randomized trials in older adults found that progressive resistance training — exercise against a load that is gradually increased — had a large positive effect on muscle strength, a small improvement in overall physical ability, and better performance on everyday tasks such as getting up from a chair.[5] Serious adverse events were rare, although minor muscle and joint complaints were common and were not always well recorded.[5]
In practice that means training the big muscles of the legs, hips, back and arms, not squeezing a grip trainer. Grip is the gauge, not the goal.
If you have a joint problem, heart disease or another condition, check with your doctor before starting a new training program.
References
- Leong DP, Teo KK, Rangarajan S, et al. Prognostic value of grip strength: findings from the Prospective Urban Rural Epidemiology (PURE) study. Lancet. 2015;386(9990):266-273. doi:10.1016/S0140-6736(14)62000-6
- Celis-Morales CA, Welsh P, Lyall DM, et al. Associations of grip strength with cardiovascular, respiratory, and cancer outcomes and all cause mortality: prospective cohort study of half a million UK Biobank participants. BMJ. 2018;361:k1651. doi:10.1136/bmj.k1651
- Cruz-Jentoft AJ, Bahat G, Bauer J, et al. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019;48(1):16-31. doi:10.1093/ageing/afy169
- Chen LK, Woo J, Assantachai P, et al. Asian Working Group for Sarcopenia: 2019 Consensus Update on Sarcopenia Diagnosis and Treatment. J Am Med Dir Assoc. 2020;21(3):300-307.e2. doi:10.1016/j.jamda.2019.12.012
- Liu CJ, Latham NK. Progressive resistance strength training for improving physical function in older adults. Cochrane Database Syst Rev. 2009;(3):CD002759. doi:10.1002/14651858.CD002759.pub2